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Focus on the spectra that matter by clustering of quantification data in shotgun proteomics

In shotgun proteomics, the analysis of label-free quantification experiments is typically limited by the identification rate and the noise level in the quantitative data. This generally causes a low sensitivity in differential expression analysis. Here, we propose a quantification-first approach for...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: The, Matthew, Käll, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319958/
https://ncbi.nlm.nih.gov/pubmed/32591519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17037-3
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