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Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19

Tocilizumab has been proposed as a means of opposing hyperinflammatory responses in intensive care patients with COVID-19. Here, we briefly discuss the potentially multiple, synergistic mechanisms whereby tocilizumab might exert therapeutic activity, mostly focusing on the production of tryptophan-d...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Belladonna, Maria Laura, Orabona, Ciriana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319082/
https://ncbi.nlm.nih.gov/pubmed/32636755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00959
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