Efficacy of Tocilizumab in Patients Hospitalized with Covid-19

BACKGROUND: The efficacy of interleukin-6 receptor blockade in hospitalized patients with coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is unclear. METHODS: We performed a randomized, double-blind, placebo-controlled trial involving patients with confirmed severe a...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Stone, John H., Frigault, Matthew J., Serling-Boyd, Naomi J., Fernandes, Ana D., Harvey, Liam, Foulkes, Andrea S., Horick, Nora K., Healy, Brian C., Shah, Ruta, Bensaci, Ana Maria, Woolley, Ann E., Nikiforow, Sarah, Lin, Nina, Sagar, Manish, Schrager, Harry, Huckins, David S., Axelrod, Matthew, Pincus, Michael D., Fleisher, Jorge, Sacks, Chana A., Dougan, Michael, North, Crystal M., Halvorsen, Yuan-Di, Thurber, Tara K., Dagher, Zeina, Scherer, Allison, Wallwork, Rachel S., Kim, Arthur Y., Schoenfeld, Sara, Sen, Pritha, Neilan, Tomas G., Perugino, Cory A., Unizony, Sebastian H., Collier, Deborah S., Matza, Mark A., Yinh, Janeth M., Bowman, Kathryn A., Meyerowitz, Eric, Zafar, Amna, Drobni, Zsofia D., Bolster, Marcy B., Kohler, Minna, D’Silva, Kristin M., Dau, Jonathan, Lockwood, Megan M., Cubbison, Caroline, Weber, Brittany N., Mansour, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: Massachusetts Medical Society 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646626/
https://ncbi.nlm.nih.gov/pubmed/33085857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2028836
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