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Methods to study mechanisms underlying altered hepatic drug elimination during pregnancy
Hepatic drug metabolism is a major route of drug elimination, mediated by multiple drug-metabolizing enzymes. Any changes in the rate and extent of hepatic drug metabolism can lead to altered drug efficacy or toxicity. Accumulating clinical evidence indicates that pregnancy is accompanied by changes...
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| Veröffentlicht in: | Semin Perinatol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319048/ https://ncbi.nlm.nih.gov/pubmed/32122644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semperi.2020.151228 |
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