Targeted Antitumor Mechanism of C-PC/CMC-CD55sp Nanospheres in HeLa Cervical Cancer Cells

In vitro studies had shown that C-Phycocyanin (C-PC) inhibited cervical cancer HeLa cells growth. We constructed C-PC/CMC-CD55sp nanospheres using C-PC, Carboxymethyl Chitosan (CMC), and CD55 ligand peptide (CD55sp) to allow for targeted antitumor effects against HeLa cells in vitro and in vivo. The...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Guoxiang, Xu, Xiaohui, Jiang, Liangqian, Ji, Huanhuan, Zhu, Feng, Jin, Bingnan, Han, Jingjing, Dong, Xiaolei, Yang, Fanghao, Li, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319041/
https://ncbi.nlm.nih.gov/pubmed/32636744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00906
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