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Synthesis and investigation of new Hesperadin analogues antitumor effects on HeLa cells
Hesperadin is one of the indolinones that was designed against the ATP-binding site of Aurora kinase. This molecule inhibits Aurora B kinase by phosphorylation of histone H3. In this study, new derivatives of Hesperadin containing an amide group in their structures were synthesized through sequentia...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076657/ https://ncbi.nlm.nih.gov/pubmed/25077005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-014-0111-3 |
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