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An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila

Circular RNAs (circRNAs) are abundant and accumulate with age in neurons of diverse species. However, only few circRNAs have been functionally characterized, and their role during aging has not been addressed. Here, we use transcriptome profiling during aging and find that accumulation of circRNAs i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell
Hauptverfasser: Weigelt, Carina Marianne, Sehgal, Rohan, Tain, Luke Stephen, Cheng, Jun, Eßer, Jacqueline, Pahl, André, Dieterich, Christoph, Grönke, Sebastian, Partridge, Linda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318944/
https://ncbi.nlm.nih.gov/pubmed/32592682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.06.011
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