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Extending the Specificity of DRL 72-s Behavior for Screening Antidepressant-Like Effects of Glutamatergic Clinically Validated Anxiolytic or Antidepressant Drugs in Rats
Both an agonist and its associated prodrug for metabotropic glutamate(2/3) (mGlu(2/3)) receptors demonstrated anxiolytic efficacy in large, randomized, multicenter, double-blind, placebo-controlled trials studying patients with generalized anxiety disorder (GAD). These mGlu(2/3) receptor agonists pr...
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| Publicado en: | J Pharmacol Exp Ther |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7318837/ https://ncbi.nlm.nih.gov/pubmed/32265323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264069 |
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