Comparative Pharmacokinetics of Δ(9)-Tetrahydrocannabinol in Adolescent and Adult Male Mice

We investigated the pharmacokinetic properties of Δ(9)-tetrahydrocannabinol (Δ(9)-THC), the main psychoactive constituent of cannabis, in adolescent and adult male mice. The drug was administered at logarithmically ascending doses (0.5, 1.6, and 5 mg/kg, i.p.) to pubertal adolescent (37-day-old) and...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Torrens, Alexa, Vozella, Valentina, Huff, Hannah, McNeil, Brandon, Ahmed, Faizy, Ghidini, Andrea, Mahler, Stephen V., Huestis, Marilyn A., Das, Aditi, Piomelli, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Neuropharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318794/
https://ncbi.nlm.nih.gov/pubmed/32345621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.265892
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