Population pharmacokinetic modeling of plasma Δ9‐tetrahydrocannabinol and an active and inactive metabolite following controlled smoked cannabis administration

AIMS: Population pharmacokinetic models of Δ9‐tetrahydrocannabinol (THC) have been developed for THC plasma and blood concentration data. Often, only the metabolites of THC are measurable when blood samples are obtained. Therefore, we performed a population pharmacokinetic analysis of THC, 11‐OH‐THC...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Sempio, Cristina, Huestis, Marilyn A., Mikulich‐Gilbertson, Susan K., Klawitter, Jost, Christians, Uwe, Henthorn, Thomas K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080615/
https://ncbi.nlm.nih.gov/pubmed/31747464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14170
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