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Evaluation of hydrophobic‐interaction chromatography resins for purification of antibody‐drug conjugates using a mimetic model with adjustable hydrophobicity

Antibody drug conjugates are cytotoxic pharmaceuticals, designed to destroy malignant cells. A cytotoxic molecule is attached to an antibody that binds specific to a cancer‐cell surface. Given the high toxicity of the drugs, strict safety standards have to be kept. For this reason, an antibody drug...

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Bibliografski detalji
Izdano u:J Sep Sci
Glavni autori: Müller, Egbert, Sevilla, Manuela, Endres, Patrick
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318155/
https://ncbi.nlm.nih.gov/pubmed/32160397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.201900895
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