Combination Therapy Using Benznidazole and Aspirin during the Acute Phase of Experimental Chagas Disease Prevents Cardiovascular Dysfunction and Decreases Typical Cardiac Lesions in the Chronic Phase

Chagas disease, caused by the protozoan Trypanosoma cruzi, is one of the main causes of death due to cardiomyopathy and heart failure in Latin American countries. The treatment of Chagas disease is directed at eliminating the parasite, decreasing the probability of cardiomyopathy and disrupting the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pereira, Rito Santo, Malvezi, Aparecida Donizette, Lovo-Martins, Maria Isabel, Lucchetti, Bruno Fernando Cruz, Santos, Jussevania Pereira, Tavares, Eliandro Reis, Verri, Waldiceu Aparecido, de Almeida Araújo, Eduardo José, Yamauchi, Lucy Megumi, Yamada-Ogatta, Sueli Fumie, Martins-Pinge, Marli Cardoso, Pinge-Filho, Phileno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318042/
https://ncbi.nlm.nih.gov/pubmed/32366719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00069-20
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