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Leishmanicidal Activity of an In Silico-Screened Novel Inhibitor against Ascorbate Peroxidase of Leishmania donovani

Peroxidases are a heterogeneous family of enzymes that have diverse biological functions. Ascorbate peroxidase is a redox enzyme that is reduced by trypanothione, which plays a central role in the redox defense system of Leishmania. In view of developing new and novel therapeutics, we performed in s...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Kashif, Mohammad, Paladhi, Ankush, Singh, Ranjeet, Bhattacharyya, Sankar, Hira, Sumit Kumar, Manna, Partha Pratim
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318017/
https://ncbi.nlm.nih.gov/pubmed/32366716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01766-19
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