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A novel assay for studying the involvement of blood cells in whole blood thrombin generation

BACKGROUND: Fluorogenic thrombin generation (TG) assays are commonly used to determine global coagulation phenotype in plasma. Whole blood (WB)‐TG assays reach one step closer to physiology by involving the intrinsic blood cells, but erythrocytes cause variable quenching of the fluorescence signals,...

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Detalles Bibliográficos
Publicado en:J Thromb Haemost
Autores principales: Wan, Jun, Konings, Joke, Yan, Qiuting, Kelchtermans, Hilde, Kremers, Romy, de Laat, Bas, Roest, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317846/
https://ncbi.nlm.nih.gov/pubmed/32108990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14786
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