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A novel assay for studying the involvement of blood cells in whole blood thrombin generation

BACKGROUND: Fluorogenic thrombin generation (TG) assays are commonly used to determine global coagulation phenotype in plasma. Whole blood (WB)‐TG assays reach one step closer to physiology by involving the intrinsic blood cells, but erythrocytes cause variable quenching of the fluorescence signals,...

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Détails bibliographiques
Publié dans:J Thromb Haemost
Auteurs principaux: Wan, Jun, Konings, Joke, Yan, Qiuting, Kelchtermans, Hilde, Kremers, Romy, de Laat, Bas, Roest, Mark
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317846/
https://ncbi.nlm.nih.gov/pubmed/32108990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14786
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