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A novel assay for studying the involvement of blood cells in whole blood thrombin generation

BACKGROUND: Fluorogenic thrombin generation (TG) assays are commonly used to determine global coagulation phenotype in plasma. Whole blood (WB)‐TG assays reach one step closer to physiology by involving the intrinsic blood cells, but erythrocytes cause variable quenching of the fluorescence signals,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Thromb Haemost
Hauptverfasser: Wan, Jun, Konings, Joke, Yan, Qiuting, Kelchtermans, Hilde, Kremers, Romy, de Laat, Bas, Roest, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317846/
https://ncbi.nlm.nih.gov/pubmed/32108990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14786
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