Absence of Bsep/Abcb11 attenuates MCD diet‐induced hepatic steatosis but aggravates inflammation in mice

BACKGROUND: Bile acids (BAs) regulate hepatic lipid metabolism and inflammation. Bile salt export pump (BSEP) KO mice are metabolically preconditioned with a hydrophilic BA composition protecting them from cholestasis. We hypothesize that changes in hepatic BA profile and subsequent changes in BA si...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Fuchs, Claudia D., Krivanec, Sebastian, Steinacher, Daniel, Mlitz, Veronika, Wahlström, Annika, Stahlman, Marcus, Claudel, Thierry, Scharnagl, Hubert, Stojakovic, Tatjana, Marschall, Hanns‐Ulrich, Trauner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Metabolic & Toxic Liver Diseases
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317533/
https://ncbi.nlm.nih.gov/pubmed/32141703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14423
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