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Impact of hypoxia on DNA repair and genome integrity
Hypoxia is a hallmark of the tumour microenvironment with profound effects on tumour biology, influencing cancer progression, the development of metastasis and patient outcome. Hypoxia also contributes to genomic instability and mutation frequency by inhibiting DNA repair pathways. This review summa...
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| Publicat a: | Mutagenesis |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7317153/ https://ncbi.nlm.nih.gov/pubmed/31282537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gez019 |
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