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Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy
Mitochondrial dysfunction leads to osteoarthritis (OA) and disc degeneration. Hypoxia inducible factor-1α (HIF-1α) mediated mitophagy has a protective role in several diseases. However, the underlying mechanism of HIF-1α mediated mitophagy in OA remains largely unknown. This current study was perfor...
Kaydedildi:
| Yayımlandı: | Cell Death Dis |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316774/ https://ncbi.nlm.nih.gov/pubmed/32587244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2680-0 |
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