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Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions

Chronic musculoskeletal pain affects all aspects of human life. However, mechanisms of its genetic control remain poorly understood. Genetic studies of pain are complicated by the high complexity and heterogeneity of pain phenotypes. Here, we apply principal component analysis to reduce phenotype he...

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Bibliografiske detaljer
Udgivet i:Commun Biol
Main Authors: Tsepilov, Yakov A., Freidin, Maxim B., Shadrina, Alexandra S., Sharapov, Sodbo Z., Elgaeva, Elizaveta E., Zundert, Jan van, Karssen, Lennart С., Suri, Pradeep, Williams, Frances M. K., Aulchenko, Yurii S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316754/
https://ncbi.nlm.nih.gov/pubmed/32587327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1051-9
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