Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions

Chronic musculoskeletal pain affects all aspects of human life. However, mechanisms of its genetic control remain poorly understood. Genetic studies of pain are complicated by the high complexity and heterogeneity of pain phenotypes. Here, we apply principal component analysis to reduce phenotype he...

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Vydáno v:Commun Biol
Hlavní autoři: Tsepilov, Yakov A., Freidin, Maxim B., Shadrina, Alexandra S., Sharapov, Sodbo Z., Elgaeva, Elizaveta E., Zundert, Jan van, Karssen, Lennart С., Suri, Pradeep, Williams, Frances M. K., Aulchenko, Yurii S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316754/
https://ncbi.nlm.nih.gov/pubmed/32587327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1051-9
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