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Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ(1-42)
Atypical low-oxidation-state iron phases in Alzheimer’s disease (AD) pathology are implicated in disease pathogenesis, as they may promote elevated redox activity and convey toxicity. However, the origin of low-oxidation-state iron and the pathways responsible for its formation and evolution remain...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316746/ https://ncbi.nlm.nih.gov/pubmed/32587293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67117-z |
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