Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide β-amyloid (1–42)

For decades, a link between increased levels of iron and areas of Alzheimer's disease (AD) pathology has been recognized, including AD lesions comprised of the peptide β-amyloid (Aβ). Despite many observations of this association, the relationship between Aβ and iron is poorly understood. Using...

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Autors principals: Everett, J., Céspedes, E., Shelford, L. R., Exley, C., Collingwood, J. F., Dobson, J., van der Laan, G., Jenkins, C. A., Arenholz, E., Telling, N. D.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006257/
https://ncbi.nlm.nih.gov/pubmed/24671940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0165
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