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Robust detection of oncometabolic aberrations by (1)H–(13)C heteronuclear single quantum correlation in intact biological specimens

Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted (1)H spectra of intact biological material and limiting diagnostic utility. Here,...

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Vydáno v:Commun Biol
Hlavní autoři: Barekatain, Yasaman, Yan, Victoria C., Arthur, Kenisha, Ackroyd, Jeffrey J., Khadka, Sunada, De Groot, John, Huse, Jason T., Muller, Florian L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316726/
https://ncbi.nlm.nih.gov/pubmed/32587392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1055-5
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