Leptin increases sympathetic nerve activity via induction of its own receptor in the paraventricular nucleus

Whether leptin acts in the paraventricular nucleus (PVN) to increase sympathetic nerve activity (SNA) is unclear, since PVN leptin receptors (LepR) are sparse. We show in rats that PVN leptin slowly increases SNA to muscle and brown adipose tissue, because it induces the expression of its own recept...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Shi, Zhigang, Pelletier, Nicole E, Wong, Jennifer, Li, Baoxin, Sdrulla, Andrei D, Madden, Christopher J, Marks, Daniel L, Brooks, Virginia L
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2020
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316512/
https://ncbi.nlm.nih.gov/pubmed/32538782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55357
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