Leptin increases sympathetic nerve activity via induction of its own receptor in the paraventricular nucleus

Whether leptin acts in the paraventricular nucleus (PVN) to increase sympathetic nerve activity (SNA) is unclear, since PVN leptin receptors (LepR) are sparse. We show in rats that PVN leptin slowly increases SNA to muscle and brown adipose tissue, because it induces the expression of its own recept...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Shi, Zhigang, Pelletier, Nicole E, Wong, Jennifer, Li, Baoxin, Sdrulla, Andrei D, Madden, Christopher J, Marks, Daniel L, Brooks, Virginia L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2020
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316512/
https://ncbi.nlm.nih.gov/pubmed/32538782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55357
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