Emergence of Simian Immunodeficiency Virus-Specific Cytotoxic CD4(+) T Cells and Increased Humoral Responses Correlate with Control of Rebounding Viremia in CD8-Depleted Macaques Infected with Rev-Independent Live-Attenuated Simian Immunodeficiency Virus

Indian rhesus macaques infected with the Rev-independent live-attenuated SIVmac239 strains control viremia to undetectable levels, have persistent but low cellular and humoral anti-SIV responses, and show no signs of immune deficiency. To analyze the immune mechanisms responsible for viral control,...

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Veröffentlicht in:J Immunol
Hauptverfasser: von Gegerfelt, Agneta, Valentin, Antonio, Alicea, Candido, Van Rompay, Koen K. A., Marthas, Marta L., Montefiori, David C., Pavlakis, George N., Felber, Barbara K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316374/
https://ncbi.nlm.nih.gov/pubmed/20702730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000572
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