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Implications of localized charge for human influenza A H1N1 hemagglutinin evolution: Insights from deep mutational scans
Seasonal influenza A viruses of humans evolve rapidly due to strong selection pressures from host immune responses, principally on the hemagglutinin (HA) viral surface protein. Based on mouse transmission experiments, a proposed mechanism for immune evasion consists of increased avidity to host cell...
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| Опубликовано в: : | PLoS Comput Biol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316228/ https://ncbi.nlm.nih.gov/pubmed/32584807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007892 |
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