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Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment
[Image: see text] While remdesivir has garnered much hope for its moderate anti-Covid-19 effects, its parent nucleoside, GS-441524, has been overlooked. Pharmacokinetic analysis of remdesivir evidences premature serum hydrolysis to GS-441524; GS-441524 is the predominant metabolite reaching the lung...
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| Publié dans: | ACS Med Chem Lett |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2020
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7315846/ https://ncbi.nlm.nih.gov/pubmed/32665809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00316 |
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