Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome

Enlarged early endosomes have been visualized in Alzheimer’s disease (AD) and Down syndrome (DS) using conventional confocal microscopy at a resolution corresponding to endosomal size (hundreds of nm). In order to overtake the diffraction limit, we used super-resolution structured illumination micro...

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Опубликовано в: :Acta Neuropathol Commun
Главные авторы: Botté, Alexandra, Lainé, Jeanne, Xicota, Laura, Heiligenstein, Xavier, Fontaine, Gaëlle, Kasri, Amal, Rivals, Isabelle, Goh, Pollyanna, Faklaris, Orestis, Cossec, Jack-Christophe, Morel, Etienne, Rebillat, Anne-Sophie, Nizetic, Dean, Raposo, Graça, Potier, Marie-Claude
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315513/
https://ncbi.nlm.nih.gov/pubmed/32580751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00956-z
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