Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer's disease patients

Identification of blood-based biomarkers of Alzheimer's disease (AD) remains a challenge. Neuropathological studies have identified enlarged endosomes in post-mortem brains as the earliest cellular change associated to AD. Here the presence of enlarged endosomes was investigated in peripheral b...

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Publicat a:Transl Psychiatry
Autors principals: Corlier, F, Rivals, I, Lagarde, J, Hamelin, L, Corne, H, Dauphinot, L, Ando, K, Cossec, J-C, Fontaine, G, Dorothée, G, Malaplate-Armand, C, Olivier, J-L, Dubois, B, Bottlaender, M, Duyckaerts, C, Sarazin, M, Potier, M-C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068716/
https://ncbi.nlm.nih.gov/pubmed/26151923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.87
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