Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition

It is well understood that the adaptive immune response to infectious agents includes a modulating suppressive component as well as an activating component. We now show that the very early innate response also has an immunosuppressive component. Infected cells upregulate the CD47 “don’t eat me” sign...

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Библиографические подробности
Опубликовано в: :mBio
Главные авторы: Tal, Michal Caspi, Torrez Dulgeroff, Laughing Bear, Myers, Lara, Cham, Lamin B., Mayer-Barber, Katrin D., Bohrer, Andrea C., Castro, Ehydel, Yiu, Ying Ying, Lopez Angel, Cesar, Pham, Ed, Carmody, Aaron B., Messer, Ronald J., Gars, Eric, Kortmann, Jens, Markovic, Maxim, Hasenkrug, Michaela, Peterson, Karin E., Winkler, Clayton W., Woods, Tyson A., Hansen, Paige, Galloway, Sarah, Wagh, Dhananjay, Fram, Benjamin J., Nguyen, Thai, Corey, Daniel, Kalluru, Raja Sab, Banaei, Niaz, Rajadas, Jayakumar, Monack, Denise M., Ahmed, Aijaz, Sahoo, Debashis, Davis, Mark M., Glenn, Jeffrey S., Adomati, Tom, Lang, Karl S., Weissman, Irving L., Hasenkrug, Kim J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315125/
https://ncbi.nlm.nih.gov/pubmed/32576678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01293-20
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