Changes in scaffold porosity during bone tissue engineering in perfusion bioreactors considerably affect cellular mechanical stimulation for mineralization

Bone tissue engineering (BTE) experiments in vitro have shown that fluid-induced wall shear stress (WSS) can stimulate cells to produce mineralized extracellular matrix (ECM). The application of WSS on seeded cells can be achieved through bioreactors that perfuse medium through porous scaffolds. In...

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Bibliografiske detaljer
Udgivet i:Bone Rep
Main Authors: Zhao, Feihu, Lacroix, Damien, Ito, Keita, van Rietbergen, Bert, Hofmann, Sandra
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Articles from the Special Issue on Computational Methods in Bone Research; Edited by Dr Penny Atkins and Dr Patrik Christen
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315008/
https://ncbi.nlm.nih.gov/pubmed/32613033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2020.100265
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