A multiscale computational fluid dynamics approach to simulate the micro-fluidic environment within a tissue engineering scaffold with highly irregular pore geometry

Mechanical stimulation can regulate cellular behavior, e.g., differentiation, proliferation, matrix production and mineralization. To apply fluid-induced wall shear stress (WSS) on cells, perfusion bioreactors have been commonly used in tissue engineering experiments. The WSS on cells depends on the...

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Bibliographic Details
Published in:Biomech Model Mechanobiol
Main Authors: Zhao, Feihu, Melke, Johanna, Ito, Keita, van Rietbergen, Bert, Hofmann, Sandra
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825226/
https://ncbi.nlm.nih.gov/pubmed/31201621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-019-01188-4
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