Diffusion MRI biomarkers of white matter microstructure vary nonmonotonically with increasing cerebral amyloid deposition

Beta amyloid (Aβ) accumulation is the earliest pathological marker of Alzheimer’s disease (AD), but early AD pathology also affects white matter (WM) integrity. We performed a cross-sectional study including 44 subjects (23 healthy controls and 21 MCI or early AD) that underwent simultaneous MR-PET...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Dong, Jian W, Jelescu, Ileana O., Ades-Aron, Benjamin, Novikov, Dmitry S., Friedman, Kent, Babb, James S., Osorio, Ricardo S., Galvin, James E., Shepherd, Timothy M., Fieremans, Els
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314576/
https://ncbi.nlm.nih.gov/pubmed/32111392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.01.009
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