Diffusion MRI biomarkers of white matter microstructure vary nonmonotonically with increasing cerebral amyloid deposition

Beta amyloid (Aβ) accumulation is the earliest pathological marker of Alzheimer’s disease (AD), but early AD pathology also affects white matter (WM) integrity. We performed a cross-sectional study including 44 subjects (23 healthy controls and 21 MCI or early AD) that underwent simultaneous MR-PET...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Dong, Jian W, Jelescu, Ileana O., Ades-Aron, Benjamin, Novikov, Dmitry S., Friedman, Kent, Babb, James S., Osorio, Ricardo S., Galvin, James E., Shepherd, Timothy M., Fieremans, Els
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314576/
https://ncbi.nlm.nih.gov/pubmed/32111392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.01.009
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