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Nuclei determine the spatial origin of mitotic waves

Traveling waves play an essential role in coordinating mitosis over large distances, but what determines the spatial origin of mitotic waves remains unclear. Here, we show that such waves initiate at pacemakers, regions that oscillate faster than their surroundings. In cell-free extracts of Xenopus...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Nolet, Felix E, Vandervelde, Alexandra, Vanderbeke, Arno, Piñeros, Liliana, Chang, Jeremy B, Gelens, Lendert
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314552/
https://ncbi.nlm.nih.gov/pubmed/32452767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52868
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