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Nuclei determine the spatial origin of mitotic waves

Traveling waves play an essential role in coordinating mitosis over large distances, but what determines the spatial origin of mitotic waves remains unclear. Here, we show that such waves initiate at pacemakers, regions that oscillate faster than their surroundings. In cell-free extracts of Xenopus...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Nolet, Felix E, Vandervelde, Alexandra, Vanderbeke, Arno, Piñeros, Liliana, Chang, Jeremy B, Gelens, Lendert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314552/
https://ncbi.nlm.nih.gov/pubmed/32452767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52868
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