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A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding

Microbial communities are self-controlled by repertoires of lethal agents, the antibiotics. In their turn, these antibiotics are regulated by bioscavengers that are selected in the course of evolution. Kinase-mediated phosphorylation represents one of the general strategies for the emergence of anti...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Terekhov, Stanislav S., Mokrushina, Yuliana A., Nazarov, Anton S., Zlobin, Alexander, Zalevsky, Arthur, Bourenkov, Gleb, Golovin, Andrey, Belogurov, Alexey, Osterman, Ilya A., Kulikova, Alexandra A., Mitkevich, Vladimir A., Lou, Hua Jane, Turk, Benjamin E., Wilmanns, Matthias, Smirnov, Ivan V., Altman, Sidney, Gabibov, Alexander G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314540/
https://ncbi.nlm.nih.gov/pubmed/32637600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz9861
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