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Regulatory B Cells Normalize CNS Myeloid Cell Content in a Mouse Model of Multiple Sclerosis and Promote Oligodendrogenesis and Remyelination

The unmet medical need of patients with multiple sclerosis (MS) is the inexorable loss of CNS myelin and latterly neurons leading to permanent neurologic disability. Solicitation of endogenous oligodendrocytes progenitor cells, the precursor of oligodendrocytes, to remyelinate axons may abort the on...

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Pubblicato in:J Neurosci
Autori principali: Pennati, Andrea, Nylen, Emily A., Duncan, Ian D., Galipeau, Jacques
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314404/
https://ncbi.nlm.nih.gov/pubmed/32430295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2840-19.2020
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