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Regulatory B Cells Normalize CNS Myeloid Cell Content in a Mouse Model of Multiple Sclerosis and Promote Oligodendrogenesis and Remyelination

The unmet medical need of patients with multiple sclerosis (MS) is the inexorable loss of CNS myelin and latterly neurons leading to permanent neurologic disability. Solicitation of endogenous oligodendrocytes progenitor cells, the precursor of oligodendrocytes, to remyelinate axons may abort the on...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pennati, Andrea, Nylen, Emily A., Duncan, Ian D., Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314404/
https://ncbi.nlm.nih.gov/pubmed/32430295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2840-19.2020
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