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Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species

Recent studies indicate that connexin hemichannels do not act as freely permeable non-selective pores, but they select permeants in an isoform-specific manner with cooperative, competitive and saturable kinetics. The aim of this study was to investigate whether the treatment with a mixture of IL-1β...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Sáez, Juan C., Vargas, Aníbal A., Hernández, Diego E., Ortiz, Fernando C., Giaume, Christian, Orellana, Juan A.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312936/
https://ncbi.nlm.nih.gov/pubmed/32492823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113970
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