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CAR-T Cell Therapies: An Overview of Clinical Studies Supporting Their Approved Use against Acute Lymphoblastic Leukemia and Large B-Cell Lymphomas

Chimeric Antigen Receptor (CAR)-T cell therapy is an exciting development in the field of cancer immunology, wherein immune T-cells from patients are collected, engineered to create ‘CAR’-T cells, and infused back into the same patient. Currently, two CAR-T-cell-based therapies, Tisagenlecleucel and...

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Pubblicato in:Int J Mol Sci
Autori principali: Ahmad, Aamir, Uddin, Shahab, Steinhoff, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312930/
https://ncbi.nlm.nih.gov/pubmed/32486160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113906
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