CD38 and Anti-CD38 Monoclonal Antibodies in AL Amyloidosis: Targeting Plasma Cells and beyond

Immunoglobulin light chain amyloidosis (AL amyloidosis) is a rare systemic disease characterized by monoclonal light chains (LCs) depositing in tissue as insoluble fibrils, causing irreversible tissue damage. The mechanisms involved in aggregation and deposition of LCs are not fully understood, but...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Roccatello, Dario, Fenoglio, Roberta, Sciascia, Savino, Naretto, Carla, Rossi, Daniela, Ferro, Michela, Barreca, Antonella, Malavasi, Fabio, Baldovino, Simone
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312896/
https://ncbi.nlm.nih.gov/pubmed/32531894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114129
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