CD38 and Anti-CD38 Monoclonal Antibodies in AL Amyloidosis: Targeting Plasma Cells and beyond

Immunoglobulin light chain amyloidosis (AL amyloidosis) is a rare systemic disease characterized by monoclonal light chains (LCs) depositing in tissue as insoluble fibrils, causing irreversible tissue damage. The mechanisms involved in aggregation and deposition of LCs are not fully understood, but...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Roccatello, Dario, Fenoglio, Roberta, Sciascia, Savino, Naretto, Carla, Rossi, Daniela, Ferro, Michela, Barreca, Antonella, Malavasi, Fabio, Baldovino, Simone
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312896/
https://ncbi.nlm.nih.gov/pubmed/32531894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114129
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