CD38 and Anti-CD38 Monoclonal Antibodies in AL Amyloidosis: Targeting Plasma Cells and beyond

Immunoglobulin light chain amyloidosis (AL amyloidosis) is a rare systemic disease characterized by monoclonal light chains (LCs) depositing in tissue as insoluble fibrils, causing irreversible tissue damage. The mechanisms involved in aggregation and deposition of LCs are not fully understood, but...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Roccatello, Dario, Fenoglio, Roberta, Sciascia, Savino, Naretto, Carla, Rossi, Daniela, Ferro, Michela, Barreca, Antonella, Malavasi, Fabio, Baldovino, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312896/
https://ncbi.nlm.nih.gov/pubmed/32531894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114129
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