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Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy Following Ischemic Brain Injury

NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome inhibition and autophagy induction attenuate inflammation and improve outcome in rodent models of cerebral ischemia. However, the impact of chronic stress on NLRP3 inflammasome and autophagic response to ischemia remains unknown. Proge...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Espinosa-Garcia, Claudia, Atif, Fahim, Yousuf, Seema, Sayeed, Iqbal, Neigh, Gretchen N., Stein, Donald G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312827/
https://ncbi.nlm.nih.gov/pubmed/32466385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113740
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