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Progesterone Treatment Attenuates Glycolytic Metabolism and Induces Senescence in Glioblastoma

We examined the effect of progesterone treatments on glycolytic metabolism and senescence as possible mechanisms in controlling the growth of glioblastoma multiforme (GBM). In an orthotopic mouse model, after tumor establishment, athymic nude mice received treatment with progesterone or vehicle for...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Atif, Fahim, Yousuf, Seema, Espinosa-Garcia, Claudia, Sergeeva, Elena, Stein, Donald G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353890/
https://ncbi.nlm.nih.gov/pubmed/30700763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37399-5
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