Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling Are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes)

Vertebral endplate bone marrow lesions, visualized on magnetic resonance imaging (MRI) as Modic changes (MC), are associated with chronic low back pain (cLBP). Since guidelines recommend against routine spinal MRI for cLBP in primary care, MC may be underdiagnosed. Serum biomarkers for MC would allo...

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Dudli, Stefan, Ballatori, Alexander, Bay-Jensen, Anne-Christine, McCormick, Zachary L., O’Neill, Conor W., Demir-Deviren, Sibel, Krug, Roland, Heggli, Irina, Juengel, Astrid, Karppinen, Jaro, Brunner, Florian, Farshad, Mazda, Distler, Oliver, Lotz, Jeffrey C., Fields, Aaron J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312719/
https://ncbi.nlm.nih.gov/pubmed/32471173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113791
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