Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling Are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes)

Vertebral endplate bone marrow lesions, visualized on magnetic resonance imaging (MRI) as Modic changes (MC), are associated with chronic low back pain (cLBP). Since guidelines recommend against routine spinal MRI for cLBP in primary care, MC may be underdiagnosed. Serum biomarkers for MC would allo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dudli, Stefan, Ballatori, Alexander, Bay-Jensen, Anne-Christine, McCormick, Zachary L., O’Neill, Conor W., Demir-Deviren, Sibel, Krug, Roland, Heggli, Irina, Juengel, Astrid, Karppinen, Jaro, Brunner, Florian, Farshad, Mazda, Distler, Oliver, Lotz, Jeffrey C., Fields, Aaron J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312719/
https://ncbi.nlm.nih.gov/pubmed/32471173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113791
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