Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model

The need for competent in vitro liver models for toxicological assessment persists. The differentiation of stem cells into hepatocyte-like cells (HLC) has been adopted due to its human origin and availability. Our aim was to study the usefulness of an in vitro 3D model of mesenchymal stem cell-deriv...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Cipriano, Madalena, Pinheiro, Pedro F, Sequeira, Catarina O, Rodrigues, Joana S, Oliveira, Nuno G, Antunes, Alexandra M M, Castro, Matilde, Marques, M Matilde, Pereira, Sofia A, Miranda, Joana P
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312429/
https://ncbi.nlm.nih.gov/pubmed/32503263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113998
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