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Sex differences in apolipoprotein A1 and nevirapine-induced toxicity
Nevirapine (NVP) is associated with severe liver and skin toxicity through sulfotransferase (SULT) bioactivation of the phase I metabolite 12-hydroxy-NVP [1–3]. The female sex, a well-known risk factor for NVP-induced toxicity, is associated with higher SULT expression [4] and lower plasma levels of...
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| Publicado no: | J Int AIDS Soc |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International AIDS Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224844/ https://ncbi.nlm.nih.gov/pubmed/25394082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19575 |
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